Prosperous food choices and sedentary life style synergize together for the occurrence of overweight and obesity among high risk groups of the population. Obesity is one of the major etiological risk factors for non communicable diseases including type 2 diabetes which is characterized by chronic hyperglycemia and impaired metabolism of carbohydrates, protein and fats. Type 2 diabetes is a multifactorial disease having genetics and environmental components contributing to its development. This review aims to highlight the association between type 2 diabetes, sedentary life style, dietary intake and depression.