Contact us Biomedscidirect.com to publish your International Medical journals and articles. http://www.biomedscidirect.com/contactus.php International Journal of Biological and Medical Research (IJBMR) helps to publish International Medical Journals, Medical Articles, Medical Research Journals, Medical Research Articles, Original journals, Case Report, Peer reviewed journal articles, Peer reviewed medical journals. http://www.biomedscidirect.com/aboutjournal.php Are you looking for Medical Research Articles, Medical Health Articles, Current Health Articles, Current Medical News and Topics.Log on to Biomedscidirect.com for Medical Research Articles, Medical Health Articles, Current Health Articles and Current Medical News and Topics. http://www.biomedscidirect.com/articles.php Find the Current and latest Medical Topics, Biology News Articles, Medical Issues, Current Biology Articles at Biomedscidirect.com.Get current and latest Medical Topics, Biology News Articles, Medical Issues and Current Biology Articles information. http://www.biomedscidirect.com/archives.php Register here to add or deposit items in our directory.Registered user can be able to manage items, up to the point of submitting them for Editorial Review. Successful item will be displayed if it is unsuccessful it will be returned to you with editorial comments. http://www.biomedscidirect.com/registration.php Biomedscidirect.com is an International Journal of Biological and Medical Research (IJBMR) publishes Original journals, Articles, Review Articles, Case Report and Short Report, Peer reviewed journal articles, Peer reviewed medical journals, international research journals and International medical journals articles. http://www.biomedscidirect.com/instructions.php Welcome to Biomedscidirect.com editors part which helps to create and submit and publish your international Medical Journals, Medical News Articles. http://www.biomedscidirect.com/editorswelcome.php Login - Biomedscidirect.com http://www.biomedscidirect.com/login.php There is evidence that high fat-fructose diet (HFFD) induces hepatic insulin resistance (IR), fatty liver, and oxidative stress in rats. The purpose of this study is to evaluate the inflammatory changes in HFFD-fed rat liver and the effect of Cissus quadrangularis stem extract (CQEt) on IR and inflammation in these rats. Rats were given HFFD for 60 days. http://www.biomedscidirect.com/78/inflammatory_responses_in_liver_induced_by_high_fat_plus_fructose_diet_therapeutic_potential_of_cissus_quadrangularis_stem Coronary Artery Disease (CAD) is the major cause of mortality and morbidity worldwide. It is associated with various risk factors such as age group (41 – 60 years), male gender, smoking habit and hypertension. The exact pro-oxidant and antioxidant status in patients with CAD is still not clear. http://www.biomedscidirect.com/88/homocysteine_and_oxidative_stress_markers_and_inflammation_in_patients_with_coronary_artery_disease High levels of high sensitive C-reactive protein (hs-CRP), homocysteine (Hcy) and oxidative stress are known to be associated with premature vascular disease in type 2 diabetes mellitus (DM). The aim of this study was to estimate homocysteine levels and oxidant-antioxidant status and to determine the relationship between them in type 2 diabetic patients with and without microalbuminuria. http://www.biomedscidirect.com/4/oxidant_antioxidant_status_high_sensitive_c_reactive_protein_and_homocysteine_levels_in_type_2_diabetic_patients_with_and_without_microalbuminuria A sensitive L-lactate biosensor based on redox species (K3Fe(CN)6) mediated lactate oxidase (LOx) has been fabricated on N-(3-dimethylaminopropyl)-N’-ethylcarbodiimide hydrochloride (EDC) activated Thioglycolic acid (TGA) self-assembled monolayer (SAM) on micro-device http://www.biomedscidirect.com/21/fabrication_of_l_lactate_biosensor_based_on_redox_species_mediated_lactate_oxidase_using_micro_device Ischemic heart is a leading cause of death all over the world. Therapeutic role of L-arginine in overcoming the oxidative stress during myocardial ischemia is still not clear. In the present work, effect of L- arginine supplementation to the patients of acute myocardial infarction has been studied. http://www.biomedscidirect.com/13/l_arginine_is_effective_in_scavenging_oxygen_derived_free_radicals_in_the_patients_of_ischemic_heart_diseases The relative levels of antioxidant activity, total flavonoid content, total phenolic content and reducing power of different organic and aqueous extracts sequentially extracted with hexane, dichloromethane, ethyl acetate, methanol and water of four different variety of cardamom viz. Mysore, Malabar, Vazhukka and Guatemala have been studied. http://www.biomedscidirect.com/18/chemical_composition_flavonoid_phenolic_contents_and_radical_scavenging_activity_of_four_major_varieties_of_cardamom To compare the removal efficiency for advanced glycosylation end products-peptides (AGE-P) from serum of patients with end stage renal disease (ESRD) by different type of dialysis membrane and modalities. Methods: 78 patients with ESRD were randomly divided into three groups: polysulfon membrane (F6), bichloroacetate cellulose membrane (CA150), hemophane membrane (HE). http://www.biomedscidirect.com/37/influence_of_dialysis_modalities_on_removal_efficiency_of_serum_age_peptides_determined_by_fia To study the hepatoprotective effect on ethnaolic extracts of Commiphora species and its formulation on CCl4 induced severe liver damage in Wistar Albino Rats. Introduction: Commiphora berryi, C. caudata, C. pubescens (Family: Burseraceae) is an exotic indigenous in South India but has widespread distribution in many tropical and sub-tropical countries. http://www.biomedscidirect.com/29/hepatoprotective_activity_on_commiphora_species_and_its_polyherbal_formulation Rice (Oryza sativa L.) is the important cereal food crop and model crop for plant genome analysis. Drought remains as one of the major constraints limiting rice productivity. Conventional breeding approaches are slow in progress towards developing drought tolerant rice varieties due to complex nature of drought tolerance mechanism. http://www.biomedscidirect.com/24/insilico_analysis_of_drought_tolerant_genes_in_rice The present study focuses on effect of phyllanthus amarus therapy for protection of liver in hepatitis-B through investigating liver profile enzymes, antioxidant enzymes, antioxidant vitamins and lipid peroxidation.Hepatitis-B is a global public health problem in India, and responsible for major chunk of morbidity and mortality. http://www.biomedscidirect.com/14/lipid_peroxidation_and_antioxidants_during_treatment_of_hepatitis_b_with_phyllanthus_amarus The present study evaluated the effect of Tender coconut water infusion on serum electrolytes, plasma L-Arginine, plasma renin activity and aldosterone levels on fructose-fed hypertensive rats.Studies on fructose induced hypertension have suggested that imbalance in electrolytes and renin –angiotensin-aldosterone system play an important role in the etiology. http://www.biomedscidirect.com/30/tender_coconut_water_maintains_the_level_of_electrolytes_and_renin_in_fructose_fed_hypertensive_rats To study the effect of dietary iron deficiency anemia on duration of gestation and pregnancy outcome the female albino rats of Wistar strain, with similar body weight (180-200g) were fed on iron deficient diets (30, 15, 7, 2mgFe/kg of diet) and one group on iron sufficient control diet (50 mgFe/kg of diet) for about one month. http://www.biomedscidirect.com/25/dietary_iron_deficiency_anemia_and_its_concequences_on_pregnancy_outcome_and_duration_of_gestation_in_rats The present study is a multi-dimensional approach aimed at assessing the efficacy of a polyherbal extract in combination with melatonin intake, as a safe natural anti-oxidant of the body, along with a regimen of swimming exercise. Adult albino rats were made diabetic by a single intraperitoneal injection of alloxan (120 mg / kg body weight). http://www.biomedscidirect.com/44/supplementation_with_a_polyherbal_extract_and_melatonin_together_with_exercise_effectively_reverses_diabetic_glycaemic_status_and_carbohydrate_metabolism_and_insulin_level The present investigation was carried out to evaluate the protective role of coumarin on glycoprotein metabolism in streptozotocin (STZ)-nicotinamide (NA) induced type 2 diabetic rats.The effects of coumarin on plasma and tissue glycoproteins (hexose, hexosamine, fucose and sialic acid) were determined.Methods: Coumarin was administered orally (100 mg/kg bodyweight) for 45 days to normal and diabetic rats. http://www.biomedscidirect.com/35/protective_role_of_coumarin_on_plasma_and_tissue_glycoprotein_components_in_streptozotocin_nicotinamide_induced_hyperglycemic_rats The study was carried out to ascertain the pattern of antimicrobial distribution and their antibiotic susceptibility profile from blood culture samples. The study was retrospective in nature and carried out at University of Calabar Teaching Hospital (UCTH) Calabar; data generated from blood culture specimens over a five year period http://www.biomedscidirect.com/59/microbial_isolates_from_clinical_specimens_of_blood_culture_and_their_antimicrobial_susceptibility_profiles_findings_from_an_analysis_of_3_255_blood_culture_specimens_at_a_university_teaching_hospital_in_southern_nigeria Effect of Pongamia pinnata (an indigenous plant used in Ayurvedic Medicine in India) leaf extract (PPEt) on the levels blood ammonia, and serum lipid profiles (cholesterol, triglycerides, phosphor lipids, free fatty acids) were studied for its protective effect during ammonium chloride induced hyperammonemia in Wistar rats. http://www.biomedscidirect.com/46/effect_of_pongamia_pinnata_leaves_on_serum_lipids_in_ammonium_chloride_induced_experimental_hyperammonemic_rats FDA has recently announced a box warning on clopidogrel package insert, as concomitant administration of clopidogrel along with a proton pump inhibitor leads to decrease in the effective concentration of clopidogrel active metabolite. Clopidogrel is an antiplatelet drug prescribed for the ACS; most of the time aspirin is also a co prescribed drug along with it. http://www.biomedscidirect.com/5/clopidogrel_and_proton_pump_interaction_confusion_clear_or_clear_confusion Maternal thyroid disease can affect the newborn baby leading to neonatal hyperthyroidism or hypothyroidism. Babies born to mothers with thyroid disease get thyroid function tests (TFT) done randomly irrespective of the nature of maternal thyroid disease and medication. http://www.biomedscidirect.com/38/serum_thyroid_function_tests_in_neonates_of_mothers_with_thyroid_disease Cancer is one of the most important diseases in the world. Every year about 8, 50,000 new cancer cases are diagnosed in India, resulting in about 5, 80,000 death. Cancer pain can result from the cancer itself or cancer treatment such as chemotherapy, radiation and surgery. http://www.biomedscidirect.com/20/effect_of_music_therapy_for_patients_with_cancer_pain The present paper describes the impact of thirty day’s feeding of fast food- French fries on the Lipid Profile of mice. The result obtained showed 12.30, 29.48, 25.77 and 34.66 per cent increase in Cholesterol, Triglyceride, LDL and VLDL level respectively, While 31.47 per cent decrease in HDL. http://www.biomedscidirect.com/28/fast_food_french_fries_induced_changes_in_lipid_profile Eupatorium ayapana was tested for its haemostatic effect based on its ethanomedical survey. Fresh juice and methanolic extract was evaluated for its haemostatic effect in rat model using tail bleeding time and blood clotting time. http://www.biomedscidirect.com/11/haemostatic_effect_of_fresh_juice_and_methanolic_extract_of_eupatorium_ayapana_leaves_in_rat_model Gastrointestinal stromal tumors (GISTs) constitute an important group of mesenchymal tumors of gastrointestinal tract. Sporadic coexistence of papillary renal cell carcinoma and gastrointestinal stromal tumor is known. Mutation in proto-oncogenes, related to tyrosine kinase receptor molecules are involved in both tumors. http://www.biomedscidirect.com/6/coexistence_of_conventional_renal_cell_carcinoma_with_gastrointestinal_stromal_tumor For over last two decades, the toxicological research has focussed on pesticide-induced oxidative stress (OS) as a possible mechanism of toxicity. In fact OS is an outcome of a multistep process spanning from perturbations in the balance between the levels of oxidants / prooxidants and antioxidants (both enzymatic and non-enzymatic) to tissue damage leading to onset of several disease states and finally to apoptosis. http://www.biomedscidirect.com/36/pesticides_induced_oxidative_stress_in_mammalian_systems_a_review Back ground: Gestational diabetes mellitus, characterized by glucose intolerance during pregnancy has many risk factors associated with it. Some studies have shown a strong association between smoking and glucose intolerance during pregnancy. We sought to examine the role of smoking as modifiable risk factor for gestational diabetes. http://www.biomedscidirect.com/60/smoking_a_modifiable_risk_factor_for_gestational_diabetes_a_review Background Production of Extended Spectrum Beta-Lactamase is a kind of antimicrobial resistance exhibited by bacteria which is a chronic problem in a health care set up. Obtaining knowledge about the prevalence of Extended Spectrum Beta Lactamase producing organisms would guide in therapeutic management of infections in a given environment. http://www.biomedscidirect.com/130/detection_of_extended_spectrum_beta_lactamase_producing_gram_negative_bacilli_in_urinary_isolates In order to study the aging changes of intramitochondrial RNA synthesis of mouse adreno-cortical and adreno-medullary cells, 10 groups of developing and aging mice, each consisting of 3 individuals, total 30, from fetal day 19 to postnatal newborn at day 1, 3, 9, 14, adult at month 1, 2, 6 and senescent animals at month 12 (year 1) and 24 (year 2) were injected with 3H-uridine, an RNA precursor, sacrificed 1 hr later and the adrenal tissues were fixed and processed for electron microscopic radioautography. http://www.biomedscidirect.com/123/electron_microscopic_radioautographic_study_on_mitochondrial_rna_synthesis_in_adrenal_cells_of_aging_mice ABSTRACT Nephrotic Syndrome is a consequence of an imbalance between oxidants and antioxidants. The present study aimed to assess oxidants and antioxidants status in relation to dyslipidemia in adults Nephrotic Syndrome patients and during remission. The study dealt with 75 adults diagnosed to have primary Nephrotic Syndrome (PNS) and all were given standard oral corticosteroid induction therapy and 50 normal healthy adults were kept for control. http://www.biomedscidirect.com/92/oxidant_stress_in_primary_nephrotic_syndrome_in_relation_to_dyslipidemia Aim: Low concentrations of magnesium (Mg2+) in red blood cells (RBC) have been implicated in the pathogenesis of dehydration in RBCs known to be a precipitating factor in sickle cell crisis. The present study is aimed at estimating the activities of ATPases localized on the red cell membrane, protein and intracellular red blood cell Mg2+ concentrations of normal and sickle cell patients. http://www.biomedscidirect.com/90/estimation_of_intracellular_magnesium_concentrations_and_membrane_atpase_activities_in_the_red_blood_cells_of_normal_and_sickle_cell_subjects_in_enugu_southeast_nigeria Yoga is a greatest Indian concept annunciated to the world. Accumulating evidences indicates that incidence and progression of coronary artery disease (CAD) may be modified by yoga. Free radicals play an important role in pathogenesis of tissue damage in many clinical disorders. http://www.biomedscidirect.com/31/effect_of_pranayama_practicing_on_lipid_peroxidation_and_antioxidants_in_coronary_artery_disease Phyllanthus niruri is a useful medicinal weed for herbalist and it holds a reputed position in both Ayurvedic and Unani system of medicine. The aim of this work was to evaluate the chemopreventive effect of hydro-alcoholic extract of the whole plant of Phyllanthus niruri, in 7-9 weeks old male Swiss albino mice http://www.biomedscidirect.com/41/chemopreventive_effect_of_phyllanthus_niruri_on_dmba_induced_skin_papillomagenesis_in_swiss_albino_mice Due to the conflicting nature of the role of nitric oxide in pregnancy induced hypertension, we had undertaken this study to estimate the levels of nitric oxide, cyclic GMP and calcium in order to follow the signal transduction pathway in PIH at different periods of gestation. Venous samples were obtained from 40 pregnant women with diagnosed PIH (study group) and 20 healthy pregnant women (control group) at 28 weeks http://www.biomedscidirect.com/125/nitric_oxide_cyclic_gmp_signal_transudation_pathway_in_pregnancy_induced_hypertension To evaluate the changes in the activities of digestive enzymes activities of silkworm supplemented with Indian bean (Dolichos lablab). Method: Finely powdered Dolichos lablab was dissolved in distilled water and diluted to 2.5 %, 5 %, 7.5 % and 10 % concentrations. Fresh mulberry leaves (Morus alba L.) were sprayed by each concentration and were fed to silkworms, from 3rd to 5th instar, five feedings/day. http://www.biomedscidirect.com/73/studies_on_the_changes_in_the_activities_of_digestive_enzymes_in_the_midgut_of_silkworm_bombyx_mori_l_lepidoptera_bombycidae_fed_with_mulberry_leaves_supplemented_with_indian_bean_dolichos_lablab Urinary tract infection is often not assumed to be a common clinical finding among children by clinicians. The study was therefore set up to ascertain the antimicrobial susceptibility patterns of bacteria recovered from urine of pre-school children with significant bacteriuria. http://www.biomedscidirect.com/126/a_survey_of_antimicrobial_susceptibility_patterns_of_bacterial_isolates_from_community_acquired_significant_bacteriuria_among_pre_school_children_in_a_municipality_in_calabar Background: Severe oxidative stress has been reported in tuberculosis patients because of malnutrition and poor immunity. Knowledge of the antioxidant status and its relation to lipid peroxidation in tuberculosis patients is scarce, particularly in developing countries. The purpose of this study was to investigate the serum lipid peroxidation products and total antioxidant capacity and correlate with C-reactive protein (CRP) levels in tuberculosis patients. http://www.biomedscidirect.com/109/immunological_correlation_of_oxidative_stress_markers_in_tuberculosis_patients Under most pathological conditions there is generation of reactive oxygen species and other free radicals. An increase in the antioxidant reserves of the organism can reduce oxidative stress and some of the plant derived agents may help to reduce it. Nyctanthes arbor-tristis leaf extracts are extensively used in Indian traditional medicine. http://www.biomedscidirect.com/72/in_vitro_anti_oxidant_studies_on_ethanolic_extracts_of_leaves_and_stems_of_nyctanthes_arbor_tristis_l_night_flowering_jasmine Aging is inevitable process, characterized by diminishing functional capacity of an organism so it fails to cope up with stress. Varieties of antioxidants are suggested by researchers to reduce the adverse effects of aging. The present study was undertaken to assess the antioxidant effect of glycowithanolides, extracted from Ashwagandha (Withania somnifera) leaves on esterase activity in submandibular and sublingual salivary glands of D-galactose induced aging mice. http://www.biomedscidirect.com/74/antioxidant_effect_of_gycowithanolides_on_esterase_activity_in_salivary_glands_of_d_galactose_stressed_mice This study is directed towards investigating the ability of various forms of vitamin B12 to augment intracellular gluthathione (GSH) level as well as studying their possible protective effect against the thimerosal-inuced oxidative stress. SH-SY5Y human neuroblastoma cell culture system was used as a model for this study. Cells were acutely (60 minutes) treated with 3 different vitamin B12 derivatives (methyl-, hydroxy- and cyanocobalamin) in the presence and absence of thimerosal http://www.biomedscidirect.com/48/in_vitro_protective_effect_of_vitamin_b12_derivatives_against_thimerosal_induced_oxidative_stress_in_human_cultured_neuronal_cells_sh_sy5y In light of evidence that some complications of diabetic mellitus may be caused or exacerbated by an oxidative stress, the putative protective effect of naringin was investigated in streptozotocin-nicotinamide induced diabetic rats. Methods: Naringin was given for 42 days at a daily dose equivalent to 80 mg/kg of body weight. Lipid peroxidation levels and non-enzymic antioxidants such as vitamin C, vitamin E and glutathione were than measured in plasma. Results: Under our experimental conditions http://www.biomedscidirect.com/79/antihyperglycemic_and_antilipidperoxidative_effects_of_flavanoid_naringin_in_streptozotocin_nicotinamide_induced_diabetic_rats