Eupatorium ayapana was tested for its haemostatic effect based on its ethanomedical survey. Fresh juice and methanolic extract was evaluated for its haemostatic effect in rat model using tail bleeding time and blood clotting time. The study revealed that both fresh juice and methanolic extract decreased the bleeding time and clotting time significantly at dose of 200 mg/kg and 50 mg/kg, respectively, which confirmed the use of Eupatorium ayapana in arresting blood bleeding traditionally.