Dentistry has seen many era of revolution in past, making it more reliable and comfortable for the patients. It is undergoing yet another change in helping mankind, this time with the help of nanotechnology combined with Nonomaterial's, Biotechnology and Nanorobotics. Nanodentistry will make possible the maintenance of comprehensive oral health by employing nanotissue devices which will allow precisely controlled oral analgesia, dentine replacement therapy, permanent hypersensitivity cure, complete orthodontic realignment etc, all in single office visit.