Lipid patterns in prediabetic and diabetic patients in rural tertiary care centre

Abstract

OBJECTIVE: Dyslipidemia is an abnormal amount of lipids elevation in serum leads to hyperlipidemias (Hypercholesterolemia and Hypertriglyceredemia), which intern predisposes atherosclerosis and than triggers cardiovascular and cerebro vascular complications.The purpose of this case - control study was to corelate lipid patterns in Prediabetic and diabetic patients to non diabetic patients. Method: This study was done at the Department of Medicine, DR. PSIMS & RF foundation Chinaoutpally, A.P.India between Jan 2012 to Dec 2012. 450 patients (150 Prediabetic, 150 diabetic and 150 non diabetic patients of 75 males and 75 females in each group) above 18 years of age were included in the study. Results: High mean Cholesterol levels were 179.9 ±34.28, 207.29 ± 42.22, 232.43 ±55.88 in non diabetic, prediabetic and diabetic group respectively. High mean Triglyceride levels were 131.4 ± 63.03, 171.3± 83.06, 190.46 + 80.71 in non diabetic, prediabetic and diabetic groups respectively. Low mean HDL - Cholesterol levels were 39.77 ±10.34, 37.21 ± 8.38. 35.1 ±7.54 in non diabetic, prediabetic and diabetic groups respectively. High mean LDL - Cholesterol levels were 112.88 ±27.67, 121.87 ± 43.91, 131.96 +33.82 in non diabetic, prcdiabetic and diabetic groups respectively. Conclusions: Dyslipidemia is the commonest complication of prediabetes and diabetes mellitus and it predisposes to premature atherosclerosis causing cardiovascular and cerebro vascular complications.