Hiv replication dynamics and pharmacological interventions

Authors:Chakrakodi Narayana Varun, Furtado Zevita, Kuruvilla Thomas. S
Int J Biol Med Res. 2013; 4(4): 3726-3734  |  PDF File

Abstract

HIV (Human Immunodeficiency Virus) type 1 is a well studied retrovirus causing an immunodeficiency syndrome. Since its first discovery in 1980’s the virus has been studied with great interest and molecular detail in an attempt to find a feasible cure or vaccine. To date this has not been satisfied owing to multiple reasons. The virus studied in extreme depth has presented with immense data and often literature is available on individual proteins or steps alone and the reader is not given a full map of dynamics of HIV replication. This overview attempts to look into all parts of HIV replication as a superficial glimpse, to draw an idea on the known facts of its life cycle and the drugs currently available commercially and the one's which may be researched upon.