A comparative clinical study of different doses of esmolal to attenuate the pressor response to laryngoscopy and tracheal intubation

Authors:Suresh S.B., Ashwini
Int J Biol Med Res. 2014; 5(1): 3831-3833  |  PDF File

Abstract

Aims and objective: The study is designed to determine the effective bolous dose of esmolol which would attenuate the pressor response to laryngoscopy and tracheal intubation. Study design: This study was conducted in the department of anaesthesia in association with department of orthopaedics, surgery and gynecology from September 2011 to April 2013. This study was done to determine the effective bolous doses of esmolol which would attenuates the pressor response to laryngoscopy and tracheal intubation in the study population consisted of 100 patients who were randomly divided into four groups of 25 patients each. Results: In our study all the groups in which esmolol was used showed a decrease in mean value of systolic blood pressure and diastolic blood pressure after administration of drug. The reduction is marked in esmolol 150 mg group and less in esmolol 50 mg group. Conclusion: All the groups in which esmolol was used showed a decrease in heart rate and blood pressure. The reduction is marked in esmolol 150 mg group, less in esmolol 50 mg group, optimal in 100 mg group. So it is concluded that esmolol 100 mg is near an ideal drug for attenuation of pressor response to laryngoscopy and tracheal intubation.