Treacher Collins Syndrome (TCS) is a rare autosomal dominant disorder of craniofacial development. It is a congenital malformation involving the structures derived from the first and second branchial arches, characterized by hypoplasia of the facial bones (mandible, maxilla and zygoma) and abnormality in the shape and size of the ears and eyelids. The extent of facial deformity varies from one affected individual to another. We report a newborn with Treacher Collins Syndrome.