Fighting fat with fat: brown adipose tissue

Authors: Suchismita Panda, Manaswini Mangaraj
Int J Biol Med Res. 2014; 5(3): 4382-4386  |  PDF File

Abstract

Obesity is the most common metabolic disorder that has become a global problem. The serious clinical problems associated with obesity include an increased risk for type 2 diabetes mellitus,atherosclerosis and cancer.Understanding the origin and development of adipocyte and excess adipose tissue resulting from positive energy balance are critical to analysis and treatment of obesity. The calorie burning brown fat and inducible brown fat like adipocyte known as beige fat in adults might prove useful to play a role in fighting against obesity and reducing the metabolic diseases. Many genes, the transcriptional regulators and factors, that regulate brown and beige adipocyte biology have now been identified providing a variety of therapeutic targets for metabolic diseases.