The coexistence of neoplastic and non-neoplastic lesions in thyroid

Authors: SMITA S. SHETE, RAJENDRA B. MADANE, SAROJ A. BOLDE, GOPAL A. PANDIT, NAVNATH S. DIGHE.
Int J Biol Med Res. 2015; 6(2): 4993-4996  |  PDF File

Abstract

Goitrous thyroid lesion is postulated as precursor lesion to thyroid cancer. Thyroid cancer is the most frequently diagnosed endocrine malignancy and enlarged thyroid gland due to goitre is worldwide problem. The association of autoimmune thyroiditis including Hashimoto’s thyroiditis with thyroid neoplasms has often been reported. In the present five year retrospective study, coexistence of neoplastic lesions of thyroid among goitrous thyroid lesions and among autoimmune thyroiditis were studied. In our study one case of Follicular adenoma (1.12%), three cases of papillary carcinoma (3.36%), one case of follicular carcinoma (1.12%) and one case of medullary carcinoma(1.12%) were associated with multinodular goitre. A single case of follicular adenoma and Hurthle cell adenoma and single case of Hurthle cell carcinoma(33.33% each) were associated with chronic lymphocytic thyroiditis. Two cases of follicular adenoma (25%) were associated with Hashimoto’s thyroiditis.