Is screening of torch worthwhile in women with bad obstetric history: an observational study from himalayan hospital

Authors:Namrata Saxena, Manju Lal, Garima Mittal, Priya
Int J Biol Med Res. 2015; 6(3): 5158-5161  |  PDF File

Abstract

Abstract Aims : To evaluate the incidence of TORCH infections in pregnancy wastage in women with bad obstetric history (BOH). Methods: The study included 70 women with bad obstetric history and 35 clinically normal women with previous normal full term deliveries. Serological evaluation for TORCH infections was carried out by IgM ELISA method over a period of eight months. Results: Seropositivity of cytomegalovirus was 21.42%, Toxoplasma 15.71%, Rubella and HSV were 8.57 %, while in control group, seropositivity for Toxoplasma and Cytomegalovirus was 2.85% and for HSV 5.71%. The highest seropositivity in cases of repeated abortions was seen with Cytomegalovirus (23.33%), followed by Toxoplasma gondii (20%). In intrauterine growth retardation, Toxoplasma and Cytomegalovirus showed highest seropositivity (37.5%). In intrauterine death and preterm labour , cytomegalovirus showed highest seropositivity 38.88% and 50% respectively. Conclusion: Seropositivity is significantly higher (p=0.00002) in women with BOH than that in controls. A previous history of pregnancy wastage and the serological reaction for TORCH infections during current pregnancy must be considered while managing BOH cases so as to reduce the adverse fetal outcome.