Chronic lymphocytic leukemia in a black african man: a cameroonian case report

Authors:Raspail Carrel Founou*, Julius Nwobegahay, Regine Gandji, Cedrice Tsayem, Sandra Yopa, Martin Kuete, Luria Leslie Founou
Int J Biol Med Res. 2019; 10(1): 6669-6671  |  PDF File

Abstract

Chronic lymphocytic leukemia (CLL) is an acquired monoclonal disorder characterized by a gradual accumulation of functionally incompetent lymphocytes. It generally presents a clonal B cells arrested in the B-cell differentiation pathway that resemble morphologically to mature lymphocytes in the peripheral blood. There is a scarcity of CLL data among sub-Saharan African countries such as Cameroon. We herein report a case of CLL that remained stable over a period of seven years in a 54 years old Black African man. The patient had no history of exposure to toxic chemicals or ionizing radiation and presented with several complaints and clinical symptoms. Clinical and laboratory investigations indicated a CLL in stage B of the Binet staging system. The dosage of chloraminophene led to a favourable outcome in the patient with the reduction of lymphocyte count, size of lymph nodes while relieving pain and improving general status and bone-marrow function of the patient.