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Evaluation of wound healing activity of “abutilon indicum” linn, in wister albino rats

Authors:Ganga suresh P, Ganesan R, Dharmalingam M
Int J Biol Med Res. 2011; 2(4): 908 - 911  |  PDF File


A study was conducted to evaluate the wound healing activity of Abutilon indicum Linn in Wister Albino Rats using two different models Viz., excision and incision. There was a significant increase in wound closure rate. The plants of Abutilon indicum was dried in a shade individually. Then the shade-dried plants were powdered to get coarse powder separately. The extraction was carried out by using solvents of increasing polarity starting from petroleum ether and ethanol respectively. All the extracts were obtained by above methods and were subjected to phytochemical studies. For the evaluation of wound healing activity, Wister albino rats were selected for this experiment. The progressive changes in the wound area were monitored by tracing the wound margin everyday. From the result, it is concluded that the petroleum ether extract of “Abutilon indicum” Linn had greater wound healing activity than the Ethanolic extract.