Prevalence of uropathogens in diabetic patients and their resistance pattern at a tertiary care centre in south india.

Authors:BV Ramana, A Chaudhury
Int J Biol Med Res. 2012; 3(1): 1433-1435  |  PDF File

Abstract

Urinary tract infection (UTI) is a common infection observed in diabetic patients. Escherichia coli are the most common bacterial pathogen causing urinary infection in diabetics, other organisms being Klebsiella pneumoniae , Proteus mirabilis and Pseudomonas aeroginosa. Among the 1200 diabetic patients, a total of 630 pathogens were isolated. Gram negative bacilli were found to be more sensitive than gram positive cocci to amikacin (65vs29%). Gram positive cocci (67%) were found to be more sensitive to cefotaxime than gram negative bacilli (55%), whereas gram negative bacilli (65%) were more sensitive than gram positive cocci (49%) to ceftizoxime. Escherichia coli was commonly isolated; the gram negative pathogens were highly sensitive to sulbactum / cefoperazone and piperacillin / tazobactum. Diabetic patients are at a high risk of development of UTIs, so continued surveillance of resistance rates among uropathogens is needed to ensure appropriate recommendations for the treatment of these infections.