A clinico-microbiological study of ventilator-associated pneumonia in a tertiary care hospital

Authors:R.M. Saldanha Dominic, H.V. Prashanth, Shalini Shenoy, Shrikala Baliga
Int J Biol Med Res. 2012; 3(2): 1651 – 1654  |  PDF File


Ventilator-associated pneumonia (VAP) is one of the commonest nosocomial infection occurring in mechanically ventilated patients in the ICU. It continues to complicate the course of 7% to 41% of patients receiving continuous mechanical ventilation.This prospective study was done to determine the etiological agents of VAP and assess their antibiotic susceptibility patterns. Semi-quantitative culture of endotracheal aspirates of patients with VAP was done. In our study, 59 patients of 153 mechanically ventilated patients developed VAP. Among the causative agents, Pseudomonas, Acinetobacter and Staphylococcus aureus were found to be the commonest etiological agents in patients with VAP. Ninety-two isolates in patients with VAP were found to be multi-drug resistant pathogens. Early and appropriate antimicrobial therapy is an important goal in the setting of life-threatening infections, taking into account factors that modulate bacterial ecology and the susceptibility of causative organisms which is crucial for optimal management.