Relationship between functional mobility tests and pulse pressure in aged men: a preliminary report.

Authors:Kavita G Marita, Sandeep Kandregula, Lakshmana N Rao, Sharma YV
Int J Biol Med Res. 2012; 3(2): 1690 -1693  |  PDF File

Abstract

Aging is a biological companion of time, spares no organ or system, and in due course affects everything, from cell to thought. Blood pressure fluctuations have been associated with microvascular damage in older adults. Pulse pressure (PP), a putative marker of vascular integrity, may be associated with brain microvascular damage and age-related decline in functional mobility. Aim: The present study destined to examine the relationship between PP and functional mobility in young and older adult men with no diagnosed neurological dysfunction. Methods: The study included 50 male participants aged between 18 – 25 and 50 - 70 years. Functional mobility measures included the near tandem balance test, the six meter walk test, the sit to stand test with five repetitions and the alternate step test. Results: Older participants performed significantly worse than the younger participants in all of the functional mobility tests (p < 0.05). Correlation analyses examined the relationship between ankle pulse pressure (PP) [systolic blood pressure (SBP) – diastolic blood pressure (DBP)], age, and mobility tests. Significant correlations were found within the older group among all the functional mobility tests scores. Conclusion: Raised PP is more prominent in the lower limb (ankle) of aged men. Elevated ankle pulse pressure may index the impaired functional mobility with advanced age.