Clinical profile and pathology of 0varian tumour

Authors:Hiremath PB, Bahubali Gane , Meenal C, Sachin Narvekar, N.M.Bobby
Int J Biol Med Res. 2012; 3(2): 1743 – 1746  |  PDF File

Abstract

Background. Ovarian cancer is the most common fatal cancer of the reproductive tract. In India , it stands second in order of malignancy of female genital tract. Reliable means for diagnosis has not yet been discovered. The location and the complex biology of ovary make diagnosis difficult. Methods. Forty cases of ovarian malignancy admitted in gynaecology ward of our institute during the period from January 2007 to March 2011. Most of these cases were referred to our hospital from peripheral centres while the rest were picked up from OPD. In the initial part of the work up a detailed history and physical examination was done followed by appropriate investigations. Patients with borderline malignancy have been excluded from this study. Their clinical profile and histopathology were analysed. Results. The most common presenting symptom was abdominal distension ( 84%) followed by abdominal pain (60.5 %). Commonest malignant tumour found was papillary serous cystadenocarcinoma (62.5%) followed by mucinous cystadenocarcinoma (17.5%) and least was immature teratoma (2.5%). 35 cases were put on chemotherapy, 30 cases completed 6 cycles,17 patients received CAP regimen, 12 patients received Cisplatin + Cyclophosphamide (CP), 5 patients received paclitaxel + carboplatin and 1 patient received Bleomycin + Etoposide + Cysplatin(BEP). Conclusion. Percentage of malignant ovarian tumors among all gynaecological admission was 1.6 %. Abdominal distention / mass per abdomen /fullness was the most common presentation. The incidence of ovarian malignancy increases with age and peaks at 51-60 yrs. The incidence decreases as parity increases.