Can sonographic prostate volume predicts prostate specific antigen(psa) levels in blood among non prostatic carcinoma patients ?

Authors:Basawaraj N G , Arul Dasan T , Ashok kumar , Srinath MG
Int J Biol Med Res. 2012; 3(3): 1895 - 1898.  |  PDF File

Abstract

Prostatic diseases are common among aging men causing significant morbidity. Benign Prostatic Hyperplasia begins before 30 years and approximately 8% of men have histological evidence of benign prostatic hyperplasia by 40 years, 50% by 60 years and 90% by 90 years of age. prostate enlargement can cause “lower urinary tract symptoms”, which tend to interfere with quality of life. This study was to correlate and establish relation among sonologically measured prostate Volume and Prostate Specific Antigen (PSA) levels in blood. Total of 115 individuals in the age group of 43-87 years (mean age of 65.71 years) with lower urinary tract symptoms underwent transabdominal sonography for the estimation of prostate volume and prostate specific antigen levels in blood. Among 115 individuals, 35 patients (30.4%) had prostate volume 20 – 30 cc, followed by 24 patients(20.9 %) had the volume more than 50 cc. The PSA mean value was 2.2 + 1.89 ng /ml. There was significant correlation of prostate volume with Blood PSA(r = 0.415, ‘P’ <0.0001). but there was no correlation of age with prostate volume (r = 0.145, ‘P’ >0.05) . To conclude there was moderate but statistically significant correlation of prostate volume with blood PSA in non-prostatic carcinoma patients. Blood PSA can be fairly predicted by assesing the prostate volume among non prostatic carcinoma patients.