Spectrum of non fermenting gram negative bacilli infection (excluding pseudomonads ) in tertiary care hospital.

Authors:D Rajendra, BV Ramana, A Chaudhury
Int J Biol Med Res. 2012; 3(3): 1892 - 1894.  |  PDF File

Abstract

Abstract: During the one year period of a total number of 15435 samples like urine, blood, sputum, wound swabs, catheter tips were processed for culture and sensitivity tests .Among the total 9261 pathogenic isolates , only 110 were reported as NFGNB .The prevalence among the culture positive infections being 1.18% .Among 110 isolates strains ,100 strains have been Acinetobacters (90.91%), 6 strains of Alkaligenes faecalis (5.45%) and 4 strains Stenotrophomonas maltophilia(3.64%) were identified.40 isolates from blood (85%) were Acinetobacter sps. Acinetobacter baumannii has been the predominant isolate (47.27%) in particular among those from blood, urine and sputum. The three most commonly recovered clinical genera are Pseudomonas, Acinetobacter, Stenotrophomonas . Acinetobacter sps. Play significant role in the colonization and infection of hospitalized patients .This organism causing variety of nosocomial infections including bacteremia, UTI, secondary meningitis particularly ventilator associated pneumonia (VAP) in ICU patients. In recent years multidrug resistance strains of NFGNB isolates studied, showed high level antibiotic resistance pattern in particular routinely used antibiotics. Resistance to Aminoglycosides and meropenam are alarming facts, lowest resistance was noticed for cefaperazone+sulbactam combination among all the genera.