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A comparative study of fev 1, fef25-75 and pefr in early adult smokers and non smokers

Authors: Ajay K T, Balu PS,Smilee jhoncy, Danyakumar G , Sangam
Int J Biol Med Res. 2012; 3(3): 2046-2049  |  PDF File


Introduction : Cigarette smoking remains the leading cause of preventable premature morbidity and mortality in both developed and developing countries around the world. Cigarette smoking directly affects lungs whose normal functioning is essential for our survival. It is responsible for 90% of chronic obstructive pulmonary diseases, chronic bronchitis, emphysema and lung cancer. This study is undertaken to highlight the effect of smoking on lung functions of early adults and thereby help them in abstaining from smoking. Objectives : To compare the lung functions(FEV1, FEF25-75 and PEFR) of early adult smokers with that of nonsmokers. Methods : A total 200 healthy young adult subjects (100 non smokers and 100 smokers) of age group 20-40 years were selected randomly among the general population in Davangere. Forced expiratory spirograms were recorded by RMS medspiror. Parameters such as Forced expiratory volume in 1st second, Forced Expiratory Flow in the middle half of FVC and Peak Expiratory Flow Rate were assessed and analyzed using the paired ‘t’-test and ANOVA. Results : Smoking had a negative impact on lung functions when compared to non smokers and smokers showed a significantly greater percentage decline in FEV1, FEF25-75% and PEFR Conclusion : Our results suggest that young smokers within few years of starting to smoke developed changes in pulmonary functions indicating early peripheral airway narrowing and that these effects worsen progressively with continued smoking.