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Evaluation and correlation of systolic time intervals (sti’s) with autonomic functions in young adults

Authors:Rajeev Sharma, Anita S. Malhotra, Priti Kumari
Int J Biol Med Res. 2012; 3(4): 2588-2592  |  PDF File


The present study was conducted to evaluate systolic time intervals (STI) and autonomic functions in young healthy adults and to find out a correlation between STI and autonomic functions for assessment of cardiac performance in different autonomic status of different subjects. The Systolic Time Intervals namely QS2 (electromechanical systole), LVET(Left Ventricular Ejection Time), PEP (Pre-ejection Period), and LVET/PEP ratio were measured by simultaneous recording of ECG, Carotid Artery Pulse & Heart Sounds. Autonomic functions were assessed in the same subjects. Sympathetic functions were assessed by Hand Grip dynamometer Test & Cold Pressor Test while Parasympathetic functions were assessed thro’ 30:15 ratio & Valsalva ratio All the STI’s and Autonomic Function Tests were found to be in normal range. QS2 and LVET both were found to have inverse and linear correlation with heart rate which was found to be statistically significant (p= 0.001& p= 0.002 respectively). STI’s were corrected for heart rate to find out the correlation between STI’s and autonomic functions. No significant correlation between different STI’s and autonomic functions was observed. The above results indicate that under normal range of functioning, autonomic functions and systolic time intervals could be independent predictors of normal cardiovascular function.