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Cost-effective analysis of topical treatment of acne in dr.b.r.ambedkar medical college, bangalore

Authors:Padma L, Kumari Bai C*, Madan Mohan N.T, Ranjani Ramanujam, Komala R
Int J Biol Med Res. 2013; 4(2): 3210- 3214  |  PDF File


ABSTRACT: BACKGROUND: Acne is a chronic inflammatory disease of the piloseabaceous gland found on face, neck, chest and back which is caused by propionibacterium acnes. Acne is highly prevalent in adolescents and adults. This affects not just the psychological well-being of the individual, but can also have a bearing on the economic aspects of the individual as well as the family, since the treatment is prolonged (at least for 4-6 months). Currently, the topical treatment for grade I and grade II acne are retinoid, antibiotics, benzoyl peroxide, and salicylic acid. Considering these aspects, we undertook a cost-effectiveness study of acne therapy to understand the latter’s economic impact on the patient and his or her family. AIM: To study the therapeutic costs in acne and economic benefit of the therapy in tertiary care hospital. OBJECTIVE: To study the cost-effectiveness of topical drugs used in the treatment of acne. MATERIALS AND METHODS: The prescriptions from the outpatient department of dermatology in a tertiary care hospital will be reviewed between 1st June 2012 to 31st August 2012, to assess the cost-effectiveness of topical therapy for mild-to-moderate acne. RESULTS: The most economical drug for topical treatment of acne is Erythromycin. Among topical retinoids, tretinoin was the most economical option. Among combination therapy, tretinoin 0.025% + clindamycin 1% gel is preferred as it is more economical. CONCLUSION: Acne Vulgaris require prolong treatment, though Erythromycin is most cost effective, its treatment as monotherapy is limited. Thus cost is not a sole deciding factor for treatment of acne. Therefore combination therapy with Tretinoin with Clindamycin is preffered.