Schmidt syndrome; polyglandular autoimmune syndrome type 2 (pga ii): presenting as hyperkalaemic paralysis

Abstract

Abstract: A young women who was a known diabetic presented with recurrent episodes of periodic muscular weakness, which was ascending in nature and was labelled to have hyperkalaemic periodic paralysis. During current presentation patient was fully evaluated for the cause for hyperkalaemia as hyperkalaemic periodic paralysis is very rare. On evaluation patient had multiple endocrine abnormalities probably autoimmune in etiology and after ruling out pseudohypoaldosteronism, patient was diagnosed to have an autoimmune hypothyroidism and Isolated Hyporeninemic Hypoaldosteronism presenting as hyperkalaemic paralysis and was treated with fludrocortisone. Patient improved significantly and there was no recurrence of weakness over a year of follow up.