Peroxidative stress and nutrient antioxidant status in periodontal disease

Abstract

In the present communication, we report remarkably elevated levels of TBARS (Thio-barbituric reactive substances), serving as an index of lipid- peroxidation and thus free-radical mediated damage in blood of patients with periodontitis. Highly significant decrease in the levels of nutrient antioxidants- tocopherol and ascorbic acid has also been found in the patients. Our results indicate on the oxidant-antioxidant disturbances in periodontitis patients which can play an important role in pathomechanism of periodontal disease in these persons. Further study on role of antioxidants in preventing periodontitis will be continued.