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Fluoride reduces semen quality at risk level in high fluoride affected regions

Authors:Dushyant Singh Chauhan , Vivek Pratap Singh , Sandeep Tripathi , Anurag Tomar , Mukesh Tiwari , Shobha Tomar , Sandeep Kumar , Abbas Ali Mahdi
Int J Biol Med Res. 2013; 4(3): 3410-3413  |  PDF File


Remarkably interest has occurred on potential decline in the sperm quality due to contamination of fluoride in drinking water. The aim of the present study was to investigate the possible impact of fluoride exposure on semen quality. The 113 subjects (age 25-40) were selected from the high fluoride region of Rajasthan where fluoride content in ground water was more than 2.0ppm. The age matched controls were selected from the area where fluoride content was <1.5ppm. The semen samples were collected for physiological profile and oxidative stress parameters. Significant changes in semen profiles, i.e., Semen Volume, liquefaction time, viability, motility, seminal pH, seminal viscosity, sperm density and oxidative stress parameters namely lipid peroxide levels, superoxide dismutase and catalase were observed in subject as compared with the controls following remarkably changes in serum and urine fluoride concentration. On the basis of results it may safely conclude that fluoride affect the semen quality which may further affects in human reproduction.