Cases of acute pesticide poisoning (APP) account for significant morbidity and mortality worldwide, especially in developing countries. Most of the cases of pesticide poisoning in India are due to organo phosphates and organo chlorides, with recent rise in aluminium phosphide in northern parts of india.Pyrethroid poisoning is relatively rare but it will pose lot of problems in diagnosis, management, detection by analytical toxicology. Here we are reporting a fatal case of suicidal pyrethroid poisoning which is relatively rare as most of the pyrethroid poisoning cases are due to accidental or occupational exposure, from a teaching hospital in southern state of Andhra Pradesh.