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Anaesthesia management in a patient with sickle cell trait and β thalassemia trait for open reduction of fracture radius and ulna”

Authors:Preeti More, Sunita Sesai, Basavaraja
Int J Biol Med Res. 2015; 6(2): 5029-5031  |  PDF File


Sickle cell disease is associated with sickling, microvascular plugging in presence of hypoxia, acidosis, hypothermia and hypovolemia leading to destructive events in vital organs. High HbS, general anaesthesia and surgical trauma are also responsible for above conditions. Patients with sickle cell disease (SCD) may present to the anesthetist in different clinical settings like perioperative care, management of acute painful crisis and intensive therapy for acute respiratory failure. We present a case of a 19-year-old male patient with sickle cell trait and β thalassemia trait with fracture radius and ulna posted for open reduction under regional anesthesia. The importance of preoperative stabilization and careful anesthetic strategy is emphasized. Regional techniques are not contraindicated in sickle cell disease and are useful for post-operative analgesia. We describe the anaesthetic management and possible pre, intra, and postoperative problems for these patients while reviewing the recent literature.