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Evaluation of hepatitis b and c related to oral health and other risk factors: a population-based, study in karachi, pakistan.

Authors:Nazia Jameel, Rubina Ghani, Hasan Ali, Saara Ahmad, Anna A. Abbasi andf ahnoor Imran
Int J Biol Med Res. 2016; 7(1): 5354-5357  |  PDF File


Background: Patients chronically infected either with hepatitis B (HBV) or hepatitis C virus (HCV) are at increased risk of developing cirrhosis, end stage liver disease and hepatocellular carcinoma(HCC). Different risk factors were found to be associated with the transmission of these viruses in various settings. HBV and HCV transmission seems to be also acquired by non- parenteral and non-sexual routes. A large number of patients infected with HCV might have non identifical routes of viral acquisition. Pre-exposure hepatitis B vaccination and the use of standard precautions to prevent exposure to blood are the most effective strategies for preventing dental health-care personnel (DHCP) from occupational exposure to occupational infection with HBV, or HCV. Objective: The aim of this study was to identify risk factors associated with the spread of hepatitis B and C in the rural areas of the upper Sindh Province, Pakistan. Materials and Methods: A total of 496 samples were collected with the history form and all the question related to risk factors were asked and datas was collected. The blood saples were collected from individual and was tested for hepatitis B surface antigen and for hepatitis C virus antibodies by ELISA. Results: Overall, 262 samples were which met the selection criteria were evaluated. During the study we assessed different dental procedures, blood transfusion, and other risk factors and we found that, besides all-time risk of HBV and HCV infection, the dental clinic is at high risk where the rate of hepatitis infected individuals is higher. Conclusion: Dental clinic are main culprit for spreading HBV and HCV besides that there are other risk factors also by which helps in spreading HBV and HCV infection. This risk can easily be eliminated using standard precautionary measures