DRESS SYNDROME - A case report with myriad systemic manifestations

Abstract

Drug rash with eosinophilia and systemic symptoms syndrome is a severe idiosyncratic drug reaction with a long latency period. It has been described using many terms; however, drug rash with eosinophilia and systemic symptoms syndrome appears to be the most appropriate. This syndrome causes a diverse array of clinical symptoms, anywhere from 2 to 8 weeks after initiating the offending drug. We report a case of generalized macular rash, pruritis, pleural effusion and acute hepatitis secondary to amoxicillin and sulphasalazine (sulpha drugs)