Analysis of parasporin (anti-cancer) proteins of bacillus thuringiensis

Abstract

Cancer is the leading cause of death in worldwide whose treatments are costly and has different physical and emotional side effects. Parsporal inclusion proteins from B. thuringiensis having specific cytotoxic activity against specific cancer cells can be used for cancer treatment which might have relatively lower side effects and might be cost effective. We have reported in silico analysis that is physico-chemical characteristics, secondary structure, 3-D structure, motifs and phylogenetic relationship among these 19 parasporin proteins to characterize them and predict their cancer cell killing mechanism.