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Eosinophilia can serve as a diagnostic clues for helminthic infestations : a case series

Authors:G. Vaishnavadevi
Int J Biol Med Res. 2023; 14(4): 7678-7680  |  PDF File  |  DOI No.: 11.2023-66773671


Human hookworm is a helminth infection caused by the nematode parasites, Necator americanus and Ancylostoma duodenale. Globally , estimated 472 million people are infected with hookworms. Necator americanus is endemic in america, africa, southern china, and southeast asian countries . Ancylostoma duodenale is endemic in north africa, mediterranean, northern regions of India and china. N. americanus larvae infect humans by transdermal or percutaneous transmission, A. duodenale larvae can penetrate the skin , infect orally , transmammary and transplacental transmission. Assessment of the haemoglobin concentration is the first step for diagnostic purposes. Complete blood counts demonstrate the presence of eosinophilia, is a diagnostic clue for nematode infection . Mebendazole and albendazole are the treatment of choice for hookworms. We present a case series , patients predominant complaints was watery diarrhoea . Evaluation of complete blood count , stool examination and other parameters were analyzed. Patients were given treatment based on clinical history, examination and laboratory investigations. On discharge all patients were symptomatically better , haematological parameters were normal, stool microscopy revealed no ova/egg and cyst and they advised for further follow-up on outpatient basis .