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The prevalence of serological markers of viruses causing acute hepatitis in south indian population

Authors:Mohana Lakshmi T , Vaithilingam A , Franklin A , Prabhakar Reddy E
Int J Biol Med Res. 2011; 2(4): 925 – 928  |  PDF File

Abstract

The term acute hepatitis refers to a primary infection of liver by one of 5 hepatitis virus types A, B, C, D and E. There is increasing evidence for another Virus not characterized and referred to as non A, B, C,D and E hepatitis virus. Hepatitis G is one candidate and there will be others. Hepatitis may occur incidentally during the course of infections with many other viruses, but this is not included under the category of viral hepatitis. All these human hepatitis viruses are RNA viruses except for hepatitis B which is a DNA virus. Viral hepatitis is a major public health problem worldwide and an important cause of morbidity and mortality. So far no studies were done previously in coastal Andhra regarding the prevalence of various viral agents involved in acute viral hepatitis, through there were studies regarding carriage of HBSAg in these areas. Consisted of 80 individuals with jaundice and other clinical and biochemical evidences of acute viral hepatitis, who were attending to Gastroenterology, Medical, pediatrics and Gynecology departments during the period of 2005 May to 2006 April at King George Hospital. Few samples done in same day and remaining other samples done at Sri Lakshmi narayana Institute of Medical Sciences, Puducherry. Out of the 47 adults with acute viral hepatitis studied, HBV was found to be the common etiological agent in 20 people (42.5%),the next common etiological agent found in adults was hepatitis E in 14 cases (29.8%) and in combination with HAV in 4 cases (8.5%), HAV was found in 6 patients (12.76%).