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Analysis of pediatrics bone marrow aspiration results done in king hussein medical center (k.h.m.c)

Authors:Fareed TH. Haddad, Abdelrazzaq Wraikat, Rame Khasawneh
Int J Biol Med Res. 2012; 3(2): 1479 –1481  |  PDF File

Abstract

Objective: To study the results of pediatrics bone marrow aspiration (B.M.A) which were done over last three years in K.H.M.C. By clinical presentation, and laboratory diagnoses. Method and material: A retrospective analysis of all bone marrow aspirate results in children. Which were done in K.H.M.C; in a period from January 2004 to December 2006. A data collecting sheets were done which includes information of age, sex, presenting symptoms, CBC results, and bone marrow aspiration results. Both as raw results as mentioned in our abstract and as deep analyses to exclude repetition of procedure for follow up purpose in case of deferent malignancies types. Results: Around 715 results was reviewed found to have 137 results (19%) as acute lymphocytic leukemia ALL with another 73 results (10%) ALL in remission, 70 results (9.8%) as acute myeloid leukemia, 2 results (0.2%) Hodgkin disease, 8 results (1.1%) non Hodgkin lymphoma, 20 results (2.8%) as neuroblastoma, two results (0.2%) as rhabdomyosarcoma, 175 results (24.5%) as normal and malignancies in remission other than ALL. Other non malignant results were 70 results (9.8%) as idiopathic thrombocytopenic parpura ITP, 61 results (8.5%) as iron deficiency anemia IDA, 16 results (2%) for each of the following megaloblastic anemia, anemia of chronic disease, and metabolic diseases. around (1%) or less for the followings compound anemia, a plastic anemia, congenital dyserythroblastic anemia, cyclic benign neutropenia, Epstein Barr virus EBV, myelodysplastic syndrome MDS, TORCH, reactive, and hemophagocytoses. Conclusion: B.M.A is a mandatory tool for diagnoses and follow up of malignancies. Although good percent shows normal results, acute lymphoblastic leukemia was the most common amongst the malignant hematological disorders followed by acute myeloid leukemia.