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Morphological features of human thymus glands from foetal to old age

Authors:Krishna Murthy, V.Subhadra Devi
Int J Biol Med Res. 2012; 3(2): 1502-1505  |  PDF File

Abstract

ABSTRACT Thymus is a primary lymphoid organ and plays an important role in strengthening the immune system. A total of 53 thymus glands of human cadavers of both sexes, normal and abnormal individuals and pre and post natal age group were observed for morphological features. The gland was located in superior mediastinum or in both superior and anterior mediastinum. Eleven different types of cervical extensions of thymus were observed. The prenatal and prepubertal glands were pyramidal in shape while post pubertal were flat. The prenatal thymuses were pink grey to brown in color and postnatal varied from white grey to yellow. Most of the glands had two lobes while a few were with three or four. The growth of thymus was maximum at pubertal age. A regression in thymus was observed at the age of 20 years that was exaggerated at 55 years of age.