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Wells’s syndrome: a case report and review of literature.

Authors:Dinesh P Asati , Neelesh Arya , Chandramohan Kudligi
Int J Biol Med Res. 2012; 3(2): 1542-1545  |  PDF File


Abstract- Case report: A 77-years-old female presented to us with one month history of gradually progressive, painful erythematous plaque on left periorbital region. In view of clinical and histological features, a diagnosis of Wells' syndrome was estabilished. Since the patient was an elderly female, dapsone was preferred to systemic steroids for treatment. Significant improvement was noted after one month of treatment with dapsone 100 mg once daily and the plaque completely cleared in 12 weeks duration, without leaving any residual atrophy or scarring. Dapsone was stopped and there was no recurrence seen at 3 months follow-up. Conclusion: Wells’ syndrome or eosinophilic cellulitis is a very rare dermatosis and it can present with wide variety of clinical presentations and differential diagnoses. Awareness of these myriad presentations is needed for its early identification and management to save the patient from undue investigations and treatments. Also, after establishing the diagnosis, search for an underlying inflammatory or proliferative systemic disease should be performed wherever there is some associated clinical or investigation based clue.