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Smoking: a modifiable risk factor for gestational diabetes? -a review

Authors:Babushankar Ponnusha, Athimoolam Ambika,Palanisamy Pasupathi,Mohammed M.Essa
Int J Biol Med Res. 2010; 1(3): 105 - 119  |  PDF File


Back ground: Gestational diabetes mellitus, characterized by glucose intolerance during pregnancy has many risk factors associated with it. Some studies have shown a strong association between smoking and glucose intolerance during pregnancy. We sought to examine the role of smoking as modifiable risk factor for gestational diabetes. Method: A systematic review of articles published upto 2010 using pub med, Embase, Science direct along with manual search through literature contributed to the present study. We focused on studies related to the effect of smoking on gestational diabetes and heterogeneity analysis was performed. Results: We analyzed data from 39 studies and 14 were included in the review. Majority of the studies indicate smoking as dose-dependent modifiable risk factor for gestational diabetes. Other studies do not support this finding. Conclusion: On the analysis of different studies regarding smoking and gestational diabetes, Current data give enough evidence to support the fact that smoking may be considered as a modifiable risk factor for gestational diabetes.